The 2025 NFL season will open with a heavyweight showdown on Thursday, September 4, when the defending champion Philadelphia Eagles host the Dallas Cowboys.
It marks the rivals’ first Week 1 matchup in 25 years, with Philly winning that 2000 opener 41-14. The Eagles dominated Dallas in 2024, sweeping the season series and outscoring them 75-13 while Dak Prescott was sidelined.
Jalen Hurts and the Eagles now look to start their title defense with a statement against a full-strength Cowboys squad led by Prescott.
The full 2025 NFL schedule will be revealed Wednesday at 8 p.m. ET across NFL Network, NFL.com, the NFL app, and NFL+.